There are
1,568 mi
from Harlingen, TX to Appleton, WI
That's the driving distance. It would take 1 day 5 hours to go from Harlingen, Texas to Appleton, Wisconsin.
The flight distance (direct flight from Harlingen, TX to Appleton, WI) is 1,351.85 mi.
1,568 mi = 2,522.75 kms