There are
2,331 mi
from Greenville, SC to Seal Beach, CA
That's the driving distance. It would take 1 day 16 hours to go from Greenville, South Carolina to Seal Beach, California.
The flight distance (direct flight from Greenville, SC to Seal Beach, CA) is 2,029.01 mi.
2,331 mi = 3,750.84 kms