Miles between Greenville, SC and Picayune, MS

There are
585 mi
from Greenville, SC to Picayune, MS

That's the driving distance. It would take 10 hours 45 mins to go from Greenville, South Carolina to Picayune, Mississippi.

The flight distance (direct flight from Greenville, SC to Picayune, MS) is 518.27 mi.

585 mi = 941.96 kms