Miles between Greenville, SC and Jacksonville, FL

There are
387 mi
from Greenville, SC to Jacksonville, FL

That's the driving distance. It would take 7 hours 6 mins to go from Greenville, South Carolina to Jacksonville, Florida.

The flight distance (direct flight from Greenville, SC to Jacksonville, FL) is 315.27 mi.

387 mi = 623.44 kms