There are
757 mi
from Greenville, SC to Endicott, NY
That's the driving distance. It would take 14 hours 30 mins to go from Greenville, South Carolina to Endicott, New York.
The flight distance (direct flight from Greenville, SC to Endicott, NY) is 606.56 mi.
757 mi = 1,218.30 kms