Miles between Greenville, SC and Effingham, IL

There are
642 mi
from Greenville, SC to Effingham, IL

That's the driving distance. It would take 12 hours 6 mins to go from Greenville, South Carolina to Effingham, Illinois.

The flight distance (direct flight from Greenville, SC to Effingham, IL) is 449.37 mi.

642 mi = 1,032.41 kms