There are
1,425 mi
from Greenville, NC to Yankton, SD
That's the driving distance. It would take 1 day 2 hours to go from Greenville, North Carolina to Yankton, South Dakota.
The flight distance (direct flight from Greenville, NC to Yankton, SD) is 1,179.46 mi.
1,425 mi = 1.61 kms