There are
2,629 mi
from Greenville, NC to Santa Clarita, CA
That's the driving distance. It would take 1 day 22 hours to go from Greenville, North Carolina to Santa Clarita, California.
The flight distance (direct flight from Greenville, NC to Santa Clarita, CA) is 2,314.82 mi.
2,629 mi = 3.22 kms