There are
574 mi
from Greenville, NC to Poughkeepsie, NY
That's the driving distance. It would take 11 hours 28 mins to go from Greenville, North Carolina to Poughkeepsie, New York.
The flight distance (direct flight from Greenville, NC to Poughkeepsie, NY) is 459.76 mi.
574 mi = 923.75 kms