There are
2,905 mi
from Greenville, NC to Issaquah, WA
That's the driving distance. It would take 2 days 4 hours to go from Greenville, North Carolina to Issaquah, Washington.
The flight distance (direct flight from Greenville, NC to Issaquah, WA) is 2,412.94 mi.
2,905 mi = 3.22 kms