There are
504 mi
from Greenville, NC to Chillicothe, OH
That's the driving distance. It would take 9 hours 48 mins to go from Greenville, North Carolina to Chillicothe, Ohio.
The flight distance (direct flight from Greenville, NC to Chillicothe, OH) is 400.99 mi.
504 mi = 811.30 kms