There are
615 mi
from Greenville, NC to Canandaigua, NY
That's the driving distance. It would take 12 hours 36 mins to go from Greenville, North Carolina to Canandaigua, New York.
The flight distance (direct flight from Greenville, NC to Canandaigua, NY) is 502.66 mi.
615 mi = 989.95 kms