There are
573 mi
from Greensboro, NC to Madisonville, KY
That's the driving distance. It would take 10 hours 33 mins to go from Greensboro, North Carolina to Madisonville, Kentucky.
The flight distance (direct flight from Greensboro, NC to Madisonville, KY) is 435.53 mi.
573 mi = 921.96 kms