There are
412 mi
from Glendale, AZ to Simi Valley, CA
That's the driving distance. It would take 7 hours 31 mins to go from Glendale, Arizona to Simi Valley, California.
The flight distance (direct flight from Glendale, AZ to Simi Valley, CA) is 381.48 mi.
412 mi = 662.40 kms