There are
488 mi
from Gaithersburg, MD to Wyandotte, MI
That's the driving distance. It would take 9 hours 9 mins to go from Gaithersburg, Maryland to Wyandotte, Michigan.
The flight distance (direct flight from Gaithersburg, MD to Wyandotte, MI) is 376.91 mi.
488 mi = 785.47 kms