There are
1,036 mi
from Gainesville, FL to Winnetka, IL
That's the driving distance. It would take 19 hours 51 mins to go from Gainesville, Florida to Winnetka, Illinois.
The flight distance (direct flight from Gainesville, FL to Winnetka, IL) is 911.89 mi.
1,036 mi = 1.61 kms