There are
1,596 mi
from Gainesville, FL to Watertown, SD
That's the driving distance. It would take 1 day 5 hours to go from Gainesville, Florida to Watertown, South Dakota.
The flight distance (direct flight from Gainesville, FL to Watertown, SD) is 1,326.30 mi.
1,596 mi = 1.61 kms