There are
1,112 mi
from Gainesville, FL to Tonawanda, NY
That's the driving distance. It would take 21 hours 27 mins to go from Gainesville, Florida to Tonawanda, New York.
The flight distance (direct flight from Gainesville, FL to Tonawanda, NY) is 940.80 mi.
1,112 mi = 1.61 kms