There are
1,411 mi
from Gainesville, FL to South Sioux City, NE
That's the driving distance. It would take 1 day 2 hours to go from Gainesville, Florida to South Sioux City, Nebraska.
The flight distance (direct flight from Gainesville, FL to South Sioux City, NE) is 1,181.22 mi.
1,411 mi = 1.61 kms