Miles between Gainesville, FL and Opelousas, LA

There are
646 mi
from Gainesville, FL to Opelousas, LA

That's the driving distance. It would take 11 hours 57 mins to go from Gainesville, Florida to Opelousas, Louisiana.

The flight distance (direct flight from Gainesville, FL to Opelousas, LA) is 586.25 mi.

646 mi = 1,039.63 kms