Miles between Gainesville, FL and Myrtle Beach, SC

There are
421 mi
from Gainesville, FL to Myrtle Beach, SC

That's the driving distance. It would take 8 hours 17 mins to go from Gainesville, Florida to Myrtle Beach, South Carolina.

The flight distance (direct flight from Gainesville, FL to Myrtle Beach, SC) is 344.46 mi.

421 mi = 678.34 kms