There are
1,493 mi
from Gainesville, FL to Lexington, NE
That's the driving distance. It would take 1 day 3 hours to go from Gainesville, Florida to Lexington, Nebraska.
The flight distance (direct flight from Gainesville, FL to Lexington, NE) is 1,243.84 mi.
1,493 mi = 1.61 kms