There are
1,312 mi
from Gainesville, FL to La Crosse, WI
That's the driving distance. It would take 1 day to go from Gainesville, Florida to La Crosse, Wisconsin.
The flight distance (direct flight from Gainesville, FL to La Crosse, WI) is 1,093.64 mi.
1,312 mi = 1.61 kms