There are
1,075 mi
from Gainesville, FL to Ithaca, NY
That's the driving distance. It would take 21 hours 7 mins to go from Gainesville, Florida to Ithaca, New York.
The flight distance (direct flight from Gainesville, FL to Ithaca, NY) is 941.20 mi.
1,075 mi = 1.61 kms