Miles between Gainesville, FL and Columbia, SC

There are
355 mi
from Gainesville, FL to Columbia, SC

That's the driving distance. It would take 6 hours 44 mins to go from Gainesville, Florida to Columbia, South Carolina.

The flight distance (direct flight from Gainesville, FL to Columbia, SC) is 309.88 mi.

355 mi = 570.59 kms