Miles between Gainesville, FL and Cayce, SC

There are
349 mi
from Gainesville, FL to Cayce, SC

That's the driving distance. It would take 6 hours 37 mins to go from Gainesville, Florida to Cayce, South Carolina.

The flight distance (direct flight from Gainesville, FL to Cayce, SC) is 306.98 mi.

349 mi = 561.18 kms