Miles between Florence, SC and Picayune, MS

There are
729 mi
from Florence, SC to Picayune, MS

That's the driving distance. It would take 13 hours 21 mins to go from Florence, South Carolina to Picayune, Mississippi.

The flight distance (direct flight from Florence, SC to Picayune, MS) is 631.50 mi.

729 mi = 1,173.72 kms