There are
1,323 mi
from Flagstaff, AZ to Sioux Falls, SD
That's the driving distance. It would take 1 day to go from Flagstaff, Arizona to Sioux Falls, South Dakota.
The flight distance (direct flight from Flagstaff, AZ to Sioux Falls, SD) is 982.07 mi.
1,323 mi = 2,128.82 kms