Miles between Fishers, IN and Cape Girardeau, MO

There are
321 mi
from Fishers, IN to Cape Girardeau, MO

That's the driving distance. It would take 6 hours 7 mins to go from Fishers, Indiana to Cape Girardeau, Missouri.

The flight distance (direct flight from Fishers, IN to Cape Girardeau, MO) is 263.19 mi.

321 mi = 516.45 kms