There are
291 mi
from Fayetteville, NC to Clemson, SC
That's the driving distance. It would take 5 hours 35 mins to go from Fayetteville, North Carolina to Clemson, South Carolina.
The flight distance (direct flight from Fayetteville, NC to Clemson, SC) is 225.86 mi.
291 mi = 468.08 kms