There are
739 mi
from Evansville, IN to Opelousas, LA
That's the driving distance. It would take 13 hours 43 mins to go from Evansville, Indiana to Opelousas, Louisiana.
The flight distance (direct flight from Evansville, IN to Opelousas, LA) is 574.66 mi.
739 mi = 1,189.93 kms