There are
324 mi
from Evansville, IN to Chillicothe, OH
That's the driving distance. It would take 6 hours 12 mins to go from Evansville, Indiana to Chillicothe, Ohio.
The flight distance (direct flight from Evansville, IN to Chillicothe, OH) is 264.83 mi.
324 mi = 520.81 kms