There are
279 mi
from Evanston, IL to La Crosse, WI
That's the driving distance. It would take 5 hours 24 mins to go from Evanston, Illinois to La Crosse, Wisconsin.
The flight distance (direct flight from Evanston, IL to La Crosse, WI) is 216.87 mi.
279 mi = 449.10 kms