There are
2,400 mi
from Durham, NC to Twentynine Palms, CA
That's the driving distance. It would take 1 day 18 hours to go from Durham, North Carolina to Twentynine Palms, California.
The flight distance (direct flight from Durham, NC to Twentynine Palms, CA) is 2,092.49 mi.
2,400 mi = 3,863.04 kms