There are
372 mi
from Duluth, MN to Manitowoc, WI
That's the driving distance. It would take 7 hours 17 mins to go from Duluth, Minnesota to Manitowoc, Wisconsin.
The flight distance (direct flight from Duluth, MN to Manitowoc, WI) is 284.79 mi.
372 mi = 598.16 kms