There are
238 mi
from Duluth, MN to La Crosse, WI
That's the driving distance. It would take 5 hours 6 mins to go from Duluth, Minnesota to La Crosse, Wisconsin.
The flight distance (direct flight from Duluth, MN to La Crosse, WI) is 210.46 mi.
238 mi = 383.34 kms