There are
540 mi
from Dubuque, IA to Lexington, NE
That's the driving distance. It would take 9 hours 55 mins to go from Dubuque, Iowa to Lexington, Nebraska.
The flight distance (direct flight from Dubuque, IA to Lexington, NE) is 483.33 mi.
540 mi = 869.14 kms