There are
1,896 mi
from Downey, CA to Tupelo, MS
That's the driving distance. It would take 1 day 8 hours to go from Downey, California to Tupelo, Mississippi.
The flight distance (direct flight from Downey, CA to Tupelo, MS) is 1,678.01 mi.
1,896 mi = 3,052.02 kms