There are
1,542 mi
from Downey, CA to Neosho, MO
That's the driving distance. It would take 1 day 2 hours to go from Downey, California to Neosho, Missouri.
The flight distance (direct flight from Downey, CA to Neosho, MO) is 1,350 mi.
1,542 mi = 2,481.46 kms