There are
2,508 mi
from Downey, CA to Mebane, NC
That's the driving distance. It would take 1 day 20 hours to go from Downey, California to Mebane, North Carolina.
The flight distance (direct flight from Downey, CA to Mebane, NC) is 2,189.70 mi.
2,508 mi = 3.22 kms