There are
2,091 mi
from Downey, CA to Jeffersonville, IN
That's the driving distance. It would take 1 day 12 hours to go from Downey, California to Jeffersonville, Indiana.
The flight distance (direct flight from Downey, CA to Jeffersonville, IN) is 1,823.48 mi.
2,091 mi = 3.22 kms