There are
1,825 mi
from Downey, CA to Hannibal, MO
That's the driving distance. It would take 1 day 7 hours to go from Downey, California to Hannibal, Missouri.
The flight distance (direct flight from Downey, CA to Hannibal, MO) is 1,527.17 mi.
1,825 mi = 1.61 kms