There are
2,648 mi
from Downey, CA to Ephrata, PA
That's the driving distance. It would take 1 day 23 hours to go from Downey, California to Ephrata, Pennsylvania.
The flight distance (direct flight from Downey, CA to Ephrata, PA) is 2,330.92 mi.
2,648 mi = 4,261.19 kms