There are
1,598 mi
from Des Moines, IA to Twentynine Palms, CA
That's the driving distance. It would take 1 day 4 hours to go from Des Moines, Iowa to Twentynine Palms, California.
The flight distance (direct flight from Des Moines, IA to Twentynine Palms, CA) is 1,323.45 mi.
1,598 mi = 2,570.94 kms