Miles between Des Moines, IA and Tupelo, MS

There are
721 mi
from Des Moines, IA to Tupelo, MS

That's the driving distance. It would take 13 hours 43 mins to go from Des Moines, Iowa to Tupelo, Mississippi.

The flight distance (direct flight from Des Moines, IA to Tupelo, MS) is 573.22 mi.

721 mi = 1,160.25 kms