Miles between Des Moines, IA and St Charles, MO

There are
326 mi
from Des Moines, IA to St Charles, MO

That's the driving distance. It would take 6 hours 32 mins to go from Des Moines, Iowa to St Charles, Missouri.

The flight distance (direct flight from Des Moines, IA to St Charles, MO) is 253.86 mi.

326 mi = 525.08 kms