Miles between Des Moines, IA and Sikeston, MO

There are
479 mi
from Des Moines, IA to Sikeston, MO

That's the driving distance. It would take 9 hours 19 mins to go from Des Moines, Iowa to Sikeston, Missouri.

The flight distance (direct flight from Des Moines, IA to Sikeston, MO) is 390.83 mi.

479 mi = 770.12 kms