Miles between Des Moines, IA and Mayfield, KY

There are
541 mi
from Des Moines, IA to Mayfield, KY

That's the driving distance. It would take 10 hours 33 mins to go from Des Moines, Iowa to Mayfield, Kentucky.

The flight distance (direct flight from Des Moines, IA to Mayfield, KY) is 428.37 mi.

541 mi = 871.36 kms