Miles between Des Moines, IA and Manchester, MO

There are
333 mi
from Des Moines, IA to Manchester, MO

That's the driving distance. It would take 6 hours 39 mins to go from Des Moines, Iowa to Manchester, Missouri.

The flight distance (direct flight from Des Moines, IA to Manchester, MO) is 264.36 mi.

333 mi = 536.60 kms