Miles between Des Moines, IA and Lisle, IL

There are
308 mi
from Des Moines, IA to Lisle, IL

That's the driving distance. It would take 5 hours 42 mins to go from Des Moines, Iowa to Lisle, Illinois.

The flight distance (direct flight from Des Moines, IA to Lisle, IL) is 285.78 mi.

308 mi = 496.00 kms